MATERNAL HIGH-FAT DIET MODIFIES EPIGENETIC MARKS H3K27ME3 AND H3K27AC IN BONE TO REGULATE OFFSPRING OSTEOBLASTOGENESIS IN MICE

Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice

Studies from both humans and animal models indicated that maternal chronic poor-quality diet, especially a high fat diet (HFD), is significantly associated with reduced bone density and childhood fractures in offspring.When previously studied in a rat model, our data suggested that maternal HFD changes epigenetic marks such as DNA methylation and h

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Historical sensing: the spatial pattern of soundscape occurrences recorded in poems between the Tang and the Qing Dynasties amid urbanization

Abstract Tapping urban and soundscape heritage in urban forests contributes to the conservation and utility of cultural heritage.However, urban heritage and soundscapes might be damaged by urban renewal and geological changes.Poems describing urban and soundscape heritage have been poorly researched due to the obscurity, fragmentation, and inaccess

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Carcinomatous Meningitis from Unknown Primary Carcinoma

Carcinomatous meningitis (CM) occurs in 3 to 8% of cancer patients.Patients present with a focal symptom, and multifocal signs are often weboost splitter found following neurological examination.The gold standard for diagnosis remains the demonstration of carcinomatous cells in the cerebrospinal fluid on cytopathological examination.Despite the poo

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The clinical and psychological profiles of patients with hypogonadism, followed in 3 reference hospitals of Cameroon: an observational study

INTRODUCTION: Hypogonadism refers to a syndrome that results from failure of gonads to function properly.The main concern is considerable rise in morbidity, as shown by increased cardiovascular risk, infertility, osteoporosis and above all, the psychological impact on the life of the patients with hypogonadism.Judicious steroid replacement and cult

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ROLE OF AUDITOR PERFORMANCE MEDIATION IN ACCEPTANCE OF AUDITOR DYSFUNCTIONAL BEHAVIOR: ATTRIBUTION THEORY PERSPECTIVE AND ROLE THEORY

The purpose of this study is to examine and to provide empirical evidence on the influence of role conflict and organizational commitment to acceptance of auditor dysfunctional behavior mediated by the Auditor Performances.Methods of data collection using survey and obtained 83 respondents here who occupy functional positions of auditors and other

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